There are several problems that people cannot always resolve without taking any drugs. It is not a secret that some of them can cause serious consequences and others are not effective at all.
And the questions are:
- Which nootropics are the most effective and why?
- Do nootropics actually help?
There is one nootropic that safely deals with depression, anxiety, and insomnia, which is considered effective called Phenibut.
Phenibut is a derivative of GABA (gamma-Aminobutyric acid) – which is an inhibitory neurotransmitter in your CNS.
It allows to avoid stress, depression, anxiety, improve sex performance, and makes it easy to socialize by decreasing sensitivity of neurons, excessive overstimulation, and brain activity, decreasing a level of Dopamine.
Phenibut is also effectively dealing with convulsive tic and stammering.
Many serious scientific studies are dedicated to Phenibut where you can familiarize yourself with the prevalence of use, desired effects, and acute toxicity of Phenibut (e.g David R. Owen, David M. Wood, John R. H. Archer, Paul I. Dargan (December 2015) ).
To be able to treat depression Phenibut needs to cross the blood-brain barriers (BBB) and bring the active substance right into the brain.
This mission is successfully solved by Phenibut most effectively: having an additional molecular Phenyl ring, it can reach your brain by simply crossing the blood-brain barrier which even GABA can’t do.
This is obvious why Phenibut is considered to be the best neurotransmitter as of today as there is no such analog of the same level of efficiency.
Phenibut is used in space for cosmonauts starting from 1975th (about set for cosmonauts you may find here: “Space Biology and Medicine: Space and its exploration” Arnauld E. Nicogossian, 1993)
Phenibut Dosage: How To Mitigate Tolerance Issues
Many sources and medical instructions to Phenibut say that the optimal drug dosage is 500 mg to 2 g (some scientific sources report about the average dosage of 2.4 g) depending on the difficulty of problems you deal with.
In cases of serious depression, it is mainly recommended to take the dosage of 1 g to 1,5, but for anxiety and sleep problems it should be less.
But it should always be taken into account that although taking Phenibut is considered to be very safe, several cautions must be observed to minimize/avoid the side effects.
Phenibut helps you feel confident and remove shyness.
For the best results, it is quite important to understand the right dosage and related issues.
To avoid any problems related to withdrawal, the dosage needs to be determined based on your understanding of the effect you wish to get when taking Phenibut.
Later here I’ll touch on the most often Phenibut withdrawal impacts and give some valuable advice on how to avoid them.
A series of trials and several reviews give us an answer for that.
Phenibut is one of such nootropics which can effectively help you in your ordinary life to deal with stress, anxiety, and depression.
All specified symptoms are quite serious and should be properly treated in due time.
Depression itself may cause different effects preventing a normal life: losing the ability to normal and healthy sleeping, a bad mood, and feeling exhausted.
In such a situation, Phenibut can bring long-expected relief and return to your normal life. Among the most explored side effects of Phenibut are nausea, headache, fatigue, dozy, realistic and unusual dream patterns.
But in some cases, you may face more rare and unusual adverse effects mostly caused by taking improper dosage or taking Phenibut for a long period.
Also, people taking Phenibut want to be well aware of the ways to mitigate the risk of withdrawal.
The root cause of any withdrawal effects is the impact of a drug on the natural production of neurotransmitters in your brain.
Phenibut helps your brain to work in a balance without neuron overstimulation. And the brain brings your body chemistry into balance by perceiving an extra neurotransmitter from the outside.
It is a signal to your brain to produce less substance for a balance.
A withdrawal may cause a different range of symptoms from fatigue and poor appetite to rapid heart and irritating (Nelson, LS (2008). “Phenibut Withdrawal – A Novel ‘Nutritional Supplement”).
In some cases, it was documented that a dosage reduction may help to avoid further expansion of such side effects as insomnia, numbness, realistic dreams, apathy, and fatigue.
A withdrawal timeline depends on the period of taking the drug and the dosage you normally take.
It is reported that in case if the dosage of Phenibut was around 1 g a day during at least consecutive 4 days per week.
It may lead to difficulties with withdrawal expressed in a longer period required to readjust your brain to live without Phenibut.
The withdrawal strategies are mainly based on testing the right Phenibut dosage with respect to a period of taking the drug.
And rescheduling its intake with a tendency to a gradual reduction of the dose.
Phenibut Tolerance Issues: How To Mitigate Risk?
When you’ve first got a feeling that the dosage you normally take is not enough, it’s the first signal to pay the attention to Phenibut tolerance issues.
Due to the fast building up a tolerance (it may be not the case for some cases of Phenibut usage when dealing with anxiety etc. and side effects which it may cause), the drug intake should be scheduled no more than two-three times a week.
Usage according to the instructions will help you to avoid tolerance issues and to prolong a period of using the drug.
It was reported that the best way to avoid tolerance is to reduce dosage (if you plan to keep taking Phenibut).
And to SLOWLY reduce it during 2-3 weeks if you plan to stop taking Phenibut at all.
It is always a good rule to let your body and brain start carefully producing required substances in absence of Phenibut.
So again, once you have experienced tolerance, for whatever reason (anxiety relief, as an antidepressant, improving sleep, cognitive enhancer, etc.). You should decide on whether to reduce dosage or stop taking Phenibut at all, considering your health condition and possible outcomes of tolerance.
And never forget to consult your doctor whenever you take any of the smart drugs.